POLYETHYLENE GLYCOL–POLYLACTIC ACID NANOPARTICLES MODIFIED WITH CYSTEINE–ARGININE–GLUTAMIC ACID–LYSINE–ALANINE FIBRIN-HOMING PEPTIDE FOR GLIOBLASTOMA THERAPY BY ENHANCED RETENTION EFFECT

Junzhu Wu,1,2,* Jingjing Zhao,1,3,* Bo Zhang,1 Yong Qian,1 Huile Gao,1 Yuan Yu,1 Yan Wei,1 Zhi Yang,1 Xinguo Jiang,1 Zhiqing Pang1 1Key Laboratory of Smart Drug Delivery, Ministry of Education, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, 2School of Pharmacy, Dali University, Xiaguan, 3School of Pharmacy, China Pharm

Abstract The cosmic electron energy spectrum recently observed by the DAMPE experiment exhibits two interesting features, including a break around 0.9 TeV and a sharp resonance near 1.4 TeV.In this analysis, we propose a dark matter explanation to both exotic features seen by DAMPE.In our model, dark matter annihilates in the galaxy via Pool Cleane

Hydraulic cylinders play a vital role in the energy output (PTO) system of an oscillating float-type wave energy converter, whose function is to convert the mechanical energy captured by the float from the waves into hydraulic energy.The performance of the hydraulic cylinder determines the conversion efficiency of mechanical energy to hydraulic ene

Although the Eucharist is attested four times (Matthew 26:26⁻29; Mark 14:22⁻25; Luke 22:15⁻20; 1 Corinthians 11:23⁻26) in the New Testament, only two (Luke and 1 Corinthians) out of the four instances bespeak of commemorating this event (“Do this in remembrance of me„).Limiting the discussion to Mark’s iter

IntroductionEpigenetic modifications have emerged as key contributors to the enduring behavioral, molecular and epigenetic neuroadaptations during withdrawal from chronic alcohol exposure.The present study investigated the long-term consequences of chronic alcohol exposure on spatial working memory (WM) and associated changes of transcriptionally r